15thAugust to 15th September 2014
Marry Raju
Mathew, Pharm.D 5th Year
This vacation I got a chance to
participate in a summer volunteership programme for a month at the John Hopkins
Saudi Aramco Healthcare in Saudi Arabia. It was quite an experience and this is
a brief overview of what I could learn during the programme.
INPATIENT PHARMACY
The inpatient pharmacy at John
Hopkins follows an automated unit dose dispensing and distribution system.
Medicines that are entered by a physician in the patient chart are faxed to the
pharmacist (called the decentralised pharmacist) who is available on each
level; the pharmacist reviews the medical orders, does medication
reconciliation and enters the medications in the electronic medical record. Any
errors are clarified with the physician before the entry is made. Once entered,
a medicine label for each individual drug for each patient is printed
automatically in the inpatient pharmacy and the drugs are dispensed as unit
doses with a label for each drug from the pharmacy.
Most of the drugs are already
available on the patient’s floor. They are stored in an automated vendor
machine called the Pyxis Medstation ™. It is an automated dispensing system
that supports decentralised medication management (picture 1). The nurse
assigned to a particular patient can alone access the medicine for a patient.
By using a unique access code and biometric finger printing the nurse can open
the particular pocket or bin having the patient’s drug. Well, if a nurse wants
to access a controlled substance like narcotic analgesics, it’s a little more
procedural, it requires two witnesses to verify before accessing. Each time an
access is made the drug remaining is recounted and entered in the Pyxis
Medstation ™
as verification. This has benefits like improved medication safety during
dispensing and administration. As all the Pyxis Medstation ™
machine are connected to a master unit in the pharmacy, the current status of
availability and use of drug on each floor can be monitored. Not all medicines
can be stored on the floor but common medicines and patients who have a
medicine that is specific to them, is stored in a patient specific bin.
Any medicine not on the machine
is printed as a label automatically in the pharmacy and they can be replenished
every 24 hours into the Pyxis Medstation ™ from the pharmacy. A printed
label has the patient details, direction for use, expiry date and batch number.
It’s important that each unit drug whether a tablet or other formulation has a
label showing its expiry date.
CLINICAL DECISION SUPPORT SYSTEM
The electronic medical record and
computerised prescriber order entry (CPOE) are
helpful technology aids but a Clinical Decision Support System (CDSS),
has the above two components with an interactive intelligent component that can
detect drug interaction, dose range, duplication and allergies which are given
as alerts immediately when a wrong drug is entered. The Epic™
system is the most advanced CDSS available and is highly efficient as it can
assist the healthcare professionals with various decision making tasks like
correlating diagnosis with the choice of drug therapy.
CLINICAL PHARMACY SERVICE
Clinical rounds are often
multidisciplinary. Every morning the physician is accompanied by a clinical
pharmacist, dietician, nurse and other medical personnel like the respiratory
therapist. When
I asked a doctor whether they prefer a multidisciplinary ward round or not, he
said they do prefer it, as a multidisciplinary ward round facilitates the delivery of safer medications and also
enables the team to plan for a patient’s healthcare jointly. During the
programme, I had an opportunity to join clinical rounds in the chemotherapy,
cardiology and medical intensive care unit.
Some of the clinical pharmacist does the vancomycin
dosing for each patient. They also do anticoagulation monitoring service, Total
Parenteral Nutrition calculations and antibiotic dosing for renal impairment as
well as medication reconciliation. In medication reconciliation the
patient’s home medication is reconciled over the active inpatient drugs during
admission, at transfer and at discharge. Medication history interview and
discharge medication counselling are part of medication reconciliation.
COMPOUNDING UNIT PHARMACISTS
Drugs for the paediatrics and
geriatrics patients who have difficulty in ingestion are prepared as syrups in
the pharmacy especially for those dose strengths that are not available
commercially. A separate area is allotted in the pharmacy for manufacturing.
All kinds of formulations which are widely used within the hospital are
prepared here. Tablets are grinded into syrups or sometimes syrups are made
from pure raw materials. The oral medications are then aspirated as unit dose
in syringes for oral use and labelled for each patient.
OUTPATIENT PHARMACY
Usually outpatient pharmacies are
quite busy, well in this hospital they have a ticketing system. This system
keeps the patient in a queue based on the priority for their prescription and
also gives a limited time framework for each pharmacist to fill the
prescription orders. To make things smoother for the pharmacist and the patient
at the counter they have brought in the Parata™ (picture 2), an automated
dispensing system loaded with up to 100 tablets and capsules. The machine
dispenses in less than a minute, yes, it saves the time that takes in counting
out tablets/capsules and keeps the prescription filling process an error free
one too.
The outpatient pharmacy also has
a medication management clinic which deals with counselling outpatients who are
on long term care or with more than ten medications.
Drug information service
department is also a live and actively functioning service the pharmacy
provides. Journal clubs are organised
for the pharmacy interns. It was a good experience to understand how an article
is critically evaluated in a practical setting, while attending the journal
club with the Pharm.D interns. They also have knowledge sharing sessions and
case presentations.
As technology is evolving at a
faster pace, most of the works like unit packaging can be done easily with
advanced automated solutions. One such solution is the Pillpick™ robot;
it automates packing and dispensing within the inpatient pharmacy. And how does
it help a pharmacist? Most obviously, gives you more time as a pharmacist to focus
on the clinical arena with patients and deal efficiently in matters regarding
to their medications.
IV PHARMACY
Most of the IV formulations are
prepared in-house. They prepare bulk preparation for the most frequently used
drugs in the hospital as well as patient specific IV formulations and
concentrated liquid allergens for the allergy clinic. Total Parenteral
Nutrition preparations are made for each patient separately, using an automated
TPN filling machine (picture 3). Chemo drugs are reconstituted in a separate
room facilitated with negative pressure and under a vertical flow hood.
PHARMACY INFORMATICS
That’s an emerging field within
the pharmacy domain. As the name suggests, pharmacy informatics backs the many
technologically supported medical services. Here, a pharmacist deals with the
number figures that’s statistics, data mining, linguistics, CDDS programming
and CDDS system trouble shooting. It’s a wide and novel arena. Some of the
universities have now included informatics as an optional subject for their
Pharm.D programme. The pharmacists in pharmacy informatics department work
close with the pharmacy and therapeutic committee. If a change is made in the
drug formulary, the same is programmed into the CDDS by the informatics
pharmacist.
CONCLUSION
Many hospitals elsewhere in the
world, like the John Hopkins Saudi Aramco Healthcare have incorporated much
advancement both clinically and technologically to ensure the patient an
eventually error free medication therapy. It was contemplating to see how
clinical and hospital pharmacy services in many other parts of the world have
evolved over the years. I could learn and understand how clinical pharmacy
services are being practised well in a real hospital setting. This programme
gave me an experience that has really boosted my confidence on becoming a
clinical pharmacist and I feel really happy on choosing doctor of pharmacy as
my career.
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