Tuesday, December 24, 2013

Pharma Pulse




OXY-ISO LENSES FOR COLOUR BLINDNESS
Color blindness, or color vision deficiency, is the inability or decreased ability to see color, or perceive color differences, under normal lighting conditions. Color blindness affects a significant percentage of the population .It is estimated to be over 250 million colour blind people worldwide and  the most common being red green color blindness. The effects of colour vision deficiency can be mild, moderate or severe depending upon the defect. If a person has inherited colour blindness, the condition will stay the same throughout the life; it won’t get any better or worse.Now scientists have developed a lens that helps correct color-blindness, allowing people to distinguish reds and greens they previously couldn’t see, and glasses are called Oxy-Iso lenses.
 Red-green colorblindness robs health care professionals of the ability to see numerous symptoms. It can be practically impossible for colour deficient, to see veins, vasculature, pallor, cyanosis, jaundice, rashes, bruising, erythema, retinal damage, Ear and throat inflammation, blood in excretions, and even medical charts and graphs. Oxy-Iso lenses correct red-green color-deficiency in a manner consistent with the perceptual needs of doctors, nurses and other medical personnel. They filter out certain wavelengths of light and enhance others, primarily in the red part of the spectrum. It also hinders perception of concentration variations, for this reason it is also used for vein-finding by medical personnel with normal color vision.                                       



INVASIVE CATHETER SYSTEM FOR MITRAL REGURGITATION
Mitral regurgitation (MR) is common worldwide and is increasing in prevalence. As life expectancy increases, valvular heart disease is becoming more common. Management of heart disease and primarily valvular heart disease is expected to represent a significant proportion of healthcare provided to the elderly population. MR is due to the failure of anterior and posterior leaflet coaptation, leading to a regurgitation of left ventricular blood into the left atrium in systole. The standard of care for the treatment of significant MR is presently surgery. 
Patients with MR who are not the candidates for surgery due to risk of mortality have a need for treatment options that will reduce the symptoms and improve the quality of life. So the scientists have developed a device, which consists of implant catheters and the MitraClip device. The device is a permanent implant that attaches to the mitral valve leaflets. This procedure results in a double opening of the mitral valve allowing greater closure and reduces the leakiness of the valve. The device is inserted by a catheter through the femoral vein and guided into the heart. The MitraClip device is positioned by grasping both leaflets of the mitral valve. The MitraClip device is left in place and the delivery catheter is removed.
The MitraClip Delivery System is indicated for the percutaneous reduction of significant symptomatic mitral regurgitation, due to primary abnormality of the mitral apparatus, in patients who have been determined to be at prohibitive risk for mitral valve surgery.
              


MEDICAL DEVICE TO REDUCE FREQUENCY OF SEIZURE.
A chronic disorder characterized by paroxysmal brain dysfunction due to excessive neuronal discharge, and usually associated with some alteration of consciousness. People with epilepsy tend to have recurrent seizures (fits). The seizures occur because of a sudden surge of electrical activity in the brain - there is an overload of electrical activity in the brain. Epilepsy affects over 50 million people worldwide and approximately one third of these people have epilepsy that is not adequately controlled by our present treatments.
The U.S. Food and Drug Administration approved a device to help reduce the frequency of seizures in epilepsy patients who have not responded well to medications known as RNS System, which  helps reduce the frequency of seizures in epilepsy patients who have frequent, disabling, partial-onset seizures and have not responded well to medications.  The RNS Stimulator consists of a small neurostimulator implanted within the skull under the scalp. The neurostimulator detects abnormal electrical activity in the brain and responds by delivering electrical stimulation intended to normalize brain activity before the patient experiences seizure symptoms.
The RNS System is intended to interrupt brain activity before the patient experiences clinical seizures.  It is used in conjunction with drugs in individuals 18 years of age or older with partial onset seizures who have undergone diagnostic testing to identify up to two areas of the brain where seizures originate and have not responded to two or more antiepileptic medications. The RNS System is used in patients who average three or more disabling seizures per month. It has not been evaluated in patients with less frequent seizures.

by Linu Mohan.P
Asst professor

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