Pharma Pulse by Linu Mohan
DEVICE TO REPAIR OESOPHAGEAL ATRESIA
The oesophagus
is the tube that normally carries food from the mouth to the stomach.
Oesophageal atresia is a congenital defect of the digestive system in which the
oesophagus does not develop properly. Almost entirely, the upper oesophagus
ends and does not connect with the lower oesophagus and stomach.
The clinical
management of the condition varies depends on the patient condition. If the gap
between the two ends of the oesophagus is small, it will be sewn together whichcalled
primary repair. If the gap is extensive, an alternative method of surgical
repair is often preferred.
The US FDA recently
approved a device which is used to non-surgically repair the oesophagus in
infants who were born with oesophageal atresia. This device consists of two
tubes each of which consists of a magnet at its edge. One tube is inserted
through the mouth and the other through the stomach. Once in place, the
magnetic ends of the catheters attract one another and pull the ends of the
oesophagus together.
Within few days,
the gap between the upper and lower oesophagus is closed and the surrounding
tissue grows together. Within a couple of weeks, the tissue trapped between the
magnets will die and a hole will open between the two portions of the
oesophagus. This device is indicated for use in paediatric patients, up to one
year of age, with oesophageal atresia.
COLOUR CHANGING DRESSING TO ALERT INFECTION
A wound can be defined as an
injury to living tissue caused by a cut, blow, or other impact, typically one
in which the skin is cut or broken. Dressing is one of the important step in
wound care as it helps to minimize the risk of infection and protect the wound.
There are different types of wound dressing which includes adhesive bandages,
non-adhesive bandages etc.
Infection is one of the major
complications in wound healing also removing the
dressing to check for infection can be painful to the patient. Now researchers
have developed a dressing and plaster that changes colour, if an infection
arises, making it possible to check wounds without changing the dressing.
This type of dressing material consists of an indicator dye that
reacts to different pH values. Healthy skin and healed wounds usually show a pH
value of or below 5. If this value increases, shifting from the acid into the
alkaline range, it indicates complications in the healing of the wound.
The indicator colour strip turns purple, when the pH value is
between 6.5 and 8 which alerts infection is frequently present. In this way the
intelligent dressing material makes it possible to regularly check wounds from
the outside without disrupting the healing process.
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