NEW SKIN CLOSURE SYSTEM FOR WOUNDS

Pharma pulse by Linu mohan

NEW SKIN CLOSURE SYSTEM FOR WOUNDS

A surgical incision is a cut made through the skin and soft tissue to facilitate an operation or procedure. It is made as small and unobtrusive as possible to promote safe surgical conditions. Once the operation is over, surgical excisions are closed by sutures, staples, steri-strips, tissue glue, or a combination of these agents. For proper healing, the wound have to cover in a protective dressing and kept dry for a few days.

Wound dehiscence is one of the most common complications of surgical incisions. This may cause the breaking open of the surgical incision along the suture. It may be a result of poor surgical techniques such as improper suturing, over-tightened sutures or inappropriate type of sutures. When it occurs, the edges of the wound starts to separate and reopens instead of healing.

Recently scientists has come forward with new skin closure system known as  surgical adhesives, which can be utilized as an alternative or as an adjunct to conventional suture closures to help, achieve good wound tension. It consist of a self-adhering flexible mesh strip, mesh anchors and a fast-curing 2-octyl cyanoacrylate topical adhesive to quickly close and seal large incisions while forming an immediate microbial barrier to protect against infections.

The self-adhering mesh and anchor system allows for easy application and enables surgeons to close incisions faster than sutures. This will help the surgeon to handle large wounds easily. The waterproof microbial barrier reduces the risk infection, allows them to shower immediately after surgery, and the innovative anchor system improves comfort during removal. This adhesive based medical skin closure can be used in all common type of surgeries and enhances the patient comfort after the procedure and prevents surgical site infections.

 

“LIQUID BIOPSY TEST” FOR EARLY CANCER DETECTION 

Cancer, also called malignancy, is an abnormal growth of cells. There are different types of cancer, including breast cancer, skin cancer, lung cancer, colon cancer, prostate cancer, and lymphoma.  For the optimum treatment of cancer the basic aim must be its recognition at a stage so early that it can be destroyed or excised before it has time to spread to a distant structure.

The existing best method for detecting cancer is a biopsy, which means cutting out a small piece of the tumour tissue for lab analysis. But biopsies are often painful and invasive. For biopsy procedure either a developed tumor or a suspect tumor is required to collect the cell for analysis.

Recently the researchers have developed a new blood test which can  identify colorectal, breast, lung, and ovarian cancers at their earliest stages which will be useful for screening people who have an increased risk of developing cancer.

The mechanism behind the test is detection of cell free circulating tumor DNA released in to the blood as small fragments from dying tumor cells. Normally tumor cells have somatic mutations that are acquired during a person's lifetime. These mutations are present only in tumor DNA. This helps to identify whether the cell free DNA fragment is from a cancer cell.

This test will be a non-invasive test for screening and monitoring cancer, with potential to save lives by detecting cancers at their earliest and most treatable stages without any need of tumour tissue samples.